PAINEL SOMÁTICO INTEGRADO

Oncograma^®

Conheça os genes e biomarcadores analisados em cada um dos painéis direcionados e no Oncograma® Total 500.

Biomarcadores: HER2, PD-L1, DLL3, TMB, MSI

Genes DNA: AKT1, ALK, BRAF, CDKN2A, EGFR, ERBB2, FGFR1, FGFR2, FGFR3, KEAP1, KRAS, MAP2K1, MET, MTOR, NF1, NRG1, NTRK1, NTRK2, NTRK3, PIK3CA, PTEN, RET, ROS1, SMARCA4, STK11, TP53

Genes RNA: ALK, BRAF, EGFR, ERBB2, FGFR1, FGFR2, FGFR3, MET, NRG1, NTRK1, NTRK2, NTRK3, PIK3CA, RET, ROS1

Biomarcadores: HER2, PD-L1, TMB, MSI

Genes DNA: AKT1, BRCA1, BRCA2, CDH1, ERBB2, ESR1, FGFR1, FGFR2, FGFR3, GATA3, MET, NF1, NTRK1, NTRK2, NTRK3, PIK3CA, PTEN, RB1, RET, TP53

Genes RNA: BRCA1, BRCA2, ERBB2, ESR1, FGFR1, FGFR2, FGFR3, MET, NTRK1, NTRK2, NTRK3, PIK3CA, RET

Biomarcadores: HER2, TMB, MSI 

Genes DNA: APC, BRAF, ERBB2, FBXW7, FGFR1, FGFR2, FGFR3, KRAS, NF1, NRAS, NRG1, NTRK1, NTRK2, NTRK3, PIK3CA, POLD1, POLE, PTEN, RET, SMAD4, TP53

Genes RNA: BRAF, ERBB2, FGFR1, FGFR2, FGFR3, NRG1, NTRK1, NTRK2, NTRK3, PIK3CA, RET

Biomarcadores: EBV (CISH - hibridização in situ cromogênica), HER2, CLDN18.2, PD-L1, TMB, MSI

Genes DNA: BRAF, EGFR, ERBB2, ERBB3, FGFR2, KRAS, MET, NF1, NTRK1, NTRK3, PIK3CA, PTEN, RET, TP53

Genes RNA: BRAF, EGFR, ERBB2, FGFR2, MET, NTRK1, NTRK3, PIK3CA, RET

Biomarcadores: TMB, MSI

Genes DNA: ATM, BRCA1, BRCA2, BRAF, CDKN2A, ERBB2, FGFR2, KRAS, MET, NRG1, NTRK1, NTRK2, NTRK3, PALB2, PIK3CA, PTEN, RET, SMAD4, TP53

Genes RNA: BRAF, BRCA1, BRCA2, ERBB2, FGFR2, MET, NRG1, NTRK1, NTRK2, NTRK3, PIK3CA, RET

Biomarcadores: HER2, TMB, MSI

Genes DNA: BRAF, CDKN2A, ERBB2, FGFR2, IDH1, KRAS, MET, NRAS, NRG1, NTRK1, NTRK2, NTRK3, PIK3CA, PTEN, RET, TP53

Genes RNA: BRAF, ERBB2, FGFR2, MET, NRG1, NTRK1, NTRK2, NTRK3, PIK3CA, RET

Biomarcadores: TMB, MSI

Genes DNA: AR, ATM, ATR, BARD1, BRAF, BRCA1, BRCA2, BRIP1, CDK12, CHEK1, CHEK2, FANCA, FANCL, KRAS, MLH1, NRG1, NTRK1, NTRK2, NTRK3, PALB2, PPP2R1A, PTEN, RAD51B, RAD51C, RAD51D, RAD54L, RET, SPOP, TP53

Genes RNA: AR, BRAF, BRCA1, BRCA2, NRG1, NTRK1, NTRK2, NTRK3, RET

Biomarcadores: HER2, TMB, MSI

Genes DNA: AKT1, ATM, BARD1, BRCA1, BRCA2, BRIP1, CDK12, CHEK2, KRAS, NRG1, NTRK1, NTRK2, NTRK3, PALB2, PPP2R1A, PTEN, RAD51C, RAD51D, RET, TP53

Genes RNA: BRCA1, BRCA2, NRG1, NTRK1, NTRK2, NTRK3, RET

Biomarcadores: HER2, TMB, MSI

Genes DNA: AKT1, ARID1A, BRAF, BRCA2, CCNE1, CDKN2A, CTNNB1, ERBB2, FBXW7, FGFR2, FGFR3, KRAS, NF1, NTRK1, NTRK2, NTRK3, PIK3CA, POLE, PPP2R1A, PTEN, RET, TP53

Genes RNA: BRAF, BRCA2, ERBB2, FGFR2, FGFR3, NTRK1, NTRK2, NTRK3, PIK3CA, RET

Biomarcadores: HER2, PD-L1, TMB, MSI

Genes DNA: BRAF, CDKN2A, ERBB2, ERCC2, FGFR3, HRAS, KRAS, MET, NTRK1, NTRK2, NTRK3, PIK3CA, RB1, RET, TP53, TSC1

Genes RNA: BRAF, ERBB2, FGFR3, MET, NTRK1, NTRK2, NTRK3, PIK3CA, RET

Biomarcadores: TMB, MSI

Genes DNA: ALK, ARID1A, BAP1, BRAF, CDKN2A, CTNNB1, GNA11, GNAQ, HRAS, KIT, KRAS, MAP2K1, MET, MITF, NF1, NRAS, NTRK1, NTRK2, NTRK3, PIK3CA, PRKAR1A, PTEN, RET, ROS1, TERT, TP53

Genes RNA: ALK, BRAF, KIT, MET, NTRK1, NTRK2, NTRK3, PIK3CA, RET, ROS1

Biomarcadores: TMB, MSI

Genes DNA: BRAF, EIF1AX, ERBB2, FGFR2, FGFR3, KRAS, MET, NF1, NRAS, NTRK1, NTRK2, NTRK3, PAX8, PIK3CA, PPARG, RET, TERT, TP53

Genes RNA: BRAF, ERBB2, FGFR2, FGFR3, MET, NTRK1, NTRK2, NTRK3, PIK3CA, PPARG, RET

Biomarcadores: TMB, MSI, 1p/19q, metilação do promotor de MGMT

Genes DNA: ATRX, BRAF, CDKN2A, CDKN2B, EGFR, FGFR1, H3-3A, H3C2, IDH1, IDH2, MET, NF1, NTRK1, NTRK2, NTRK3, PIK3CA, TERT, TP53

Genes RNA: BRAF, EGFR, FGFR1, MET, NTRK1, NTRK2, NTRK3, PIK3CA

Biomarcadores: TMB, MSI

Genes DNA: BRAF, CDKN2A, FGFR1, KIT, KRAS, NF1, NRG1, NTRK1, NTRK2, NTRK3, PDGFRA, PIK3CA, PTEN, RET, SDHA, SDHB, SDHC, SDHD, TP53

Genes RNA: BRAF, FGFR1, KIT, NRG1, NTRK1, NTRK2, NTRK3, PDGFRA, PIK3CA, RET

Biomarcadores: TMB, MSI

Genes DNA: ALK, BCOR, BRAF, CDK4, CDKN2A, CIC, EWSR1, MDM2, MET, NF1, NTRK1, NTRK2, NTRK3, PIK3CA, PTEN, RET, TP53, TSC2

Genes RNA: ALK, BRAF, CDK4, EWSR1, MET, NTRK1, NTRK2, NTRK3, PIK3CA, RET

Biomarcadores: TMB, MSI

Genes DNA: ABL1, ALK, ATM, BCL2, BIRC3, BRAF, BTK, CARD11, CD79B, CREBBP, EZH2, KMT2A, KMT2D, MYD88, NOTCH1, NOTCH2, SF3B1, TNFRSF14, TP53, XPO1

Genes RNA: ABL1, ALK, BCL2, BRAF, KMT2A, NOTCH1, NOTCH2

Biomarcadores: TMB, MSI

Genes DNA: BRAF, CYLD, DIS3, KRAS, NRAS, TENT5C, TP53

Genes RNA: BRAF

Biomarcadores: EBV (CISH - hibridização in situ cromogênica), HER2, CLDN18.2, PD-L1, DLL3, TMB, MSI, 1p/19q, metilação do promotor de MGMT. Análise de acordo com indicação clínica.

Genes DNA: ABL1, ABL2, ABRAXAS1, ACVR1, ACVR1B, ADGRA2, AKT1, AKT2, AKT3, ALK, ALOX12B, AMER1, ANKRD11, ANKRD26, APC, AR, ARAF, ARFRP1, ARID1A, ARID1B, ARID2, ARID5B, ASXL1, ASXL2, ATM, ATR, ATRX, AURKA, AURKB, AXIN1, AXIN2, AXL, B2M, BAP1, BARD1, BBC3, BCL10, BCL2, BCL2L1, BCL2L11, BCL2L2, BCL6, BCOR, BCORL1, BCR, BIRC3, BLM, BMPR1A, BRAF, BRCA1, BRCA2, BRD4, BRIP1, BTG1, BTK, CALR, CARD11, CASP8, CBFB, CBL, CCN6, CCND1, CCND2, CCND3, CCNE1, CD274, CD276, CD74, CD79A, CD79B, CDC73, CDH1, CDK12, CDK4, CDK6, CDK8, CDKN1A, CDKN1B, CDKN2A, CDKN2B, CDKN2C, CEBPA, CENPA, CHD2, CHD4, CHEK1, CHEK2, CIC, COP1, CREBBP, CRKL, CRLF2, CSF1R, CSF3R, CSNK1A1, CTCF, CTLA4, CTNNA1, CTNNB1, CUL3, CUX1, CXCR4, CYLD, DAXX, DCUN1D1, DDR2, DDX41, DHX15, DICER1, DIS3, DNAJB1, DNMT1, DNMT3A, DNMT3B, DOT1L, E2F3, EED, EGFL7, EGFR, EIF1AX, EIF4A2, EIF4E, ELOC, EML4, EMSY, EP300, EPCAM, EPHA3, EPHA5, EPHA7, EPHB1, ERBB2, ERBB3, ERBB4, ERCC1, ERCC2, ERCC3, ERCC4, ERCC5, ERG, ERRFI1, ESR1, ETS1, ETV1, ETV4, ETV5, ETV6, EWSR1, EZH2, FANCA, FANCC, FANCD2, FANCE, FANCF, FANCG, FANCI, FANCL, FAS, FAT1, FBXW7, FGF1, FGF10, FGF14, FGF19, FGF2, FGF23, FGF3, FGF4, FGF5, FGF6, FGF7, FGF8, FGF9, FGFR1, FGFR2, FGFR3, FGFR4, FH, FLCN, FLI1, FLT1, FLT3, FLT4, FOXA1, FOXL2, FOXO1, FOXP1, FRS2, FUBP1, FYN, GABRA6, GATA1, GATA2, GATA3, GATA4, GATA6, GEN1, GID4, GLI1, GNA11, GNA13, GNAQ, GNAS, GPS2, GREM1, GRIN2A, GRM3, GSK3B, H1-2, H2BC5, H3-3A, H3-3B, H3-4, H3-5, H3C1, H3C10, H3C11, H3C12, H3C13, H3C14, H3C15, H3C2, H3C3, H3C4, H3C6, H3C7, H3C8, HGF, HLA-A, HNF1A, HNRNPK, HOXB13, HRAS, HSD3B1, HSP90AA1, ICOSLG, ID3, IDH1, IDH2, IFNGR1, IGF1, IGF1R, IGF2, IKBKE, IKZF1, IL10, IL7R, INHA, INHBA, INPP4A, INPP4B, INSR, IRF2, IRF4, IRS1, IRS2, JAK1, JAK2, JAK3, JUN, KAT6A, KDM5A, KDM5C, KDM6A, KDR, KEAP1, KEL, KIF5B, KIT, KLF4, KLHL6, KMT2A, KMT2B, KMT2C, KMT2D, KRAS, LAMP1, LATS1, LATS2, LMO1, LRP1B, LYN, LZTR1, MAGI2, MALT1, MAP2K1, MAP2K2, MAP2K4, MAP3K1, MAP3K13, MAP3K14, MAP3K4, MAPK1, MAPK3, MAX, MCL1, MDC1, MDM2, MDM4, MED12, MEF2B, MEN1, MET, MGA, MITF, MLH1, MLLT3, MPL, MRE11, MSH2, MSH3, MSH6, MST1, MST1R, MTOR, MUTYH, MYB, MYC, MYCL, MYCN, MYD88, MYOD1, NAB2, NBN, NCOA3, NCOR1, NEGR1, NF1, NF2, NFE2L2, NFKBIA, NKX2-1, NKX3-1, NOTCH1, NOTCH2, NOTCH3, NOTCH4, NPM1, NRAS, NRG1, NSD1, NTRK1, NTRK2, NTRK3, NUP93, NUTM1, PAK1, PAK3, PAK5, PALB2, PARP1, PAX3, PAX5, PAX7, PAX8, PBRM1, PDCD1, PDCD1LG2, PDGFRA, PDGFRB, PDK1, PDPK1, PGR, PHF6, PHOX2B, PIK3C2B, PIK3C2G, PIK3C3, PIK3CA, PIK3CB, PIK3CD, PIK3CG, PIK3R1, PIK3R2, PIK3R3, PIM1, PLCG2, PLK2, PMAIP1, PMS1, PMS2, PNRC1, POLD1, POLE, PPARG, PPM1D, PPP2R1A, PPP2R2A, PPP6C, PRDM1, PREX2, PRKAR1A, PRKCI, PRKDC, PRKN, PRSS8, PTCH1, PTEN, PTPN11, PTPRD, PTPRS, PTPRT, QKI, RAB35, RAC1, RAD21, RAD50, RAD51, RAD51B, RAD51C, RAD51D, RAD52, RAD54L, RAF1, RANBP2, RARA, RASA1, RB1, RBM10, RECQL4, REL, RET, RHEB, RHOA, RICTOR, RIT1, RNF43, ROS1, RPS6KA4, RPS6KB1, RPS6KB2, RPTOR, RUNX1, RUNX1T1, RYBP, SDHA, SDHAF2, SDHB, SDHC, SDHD, SETBP1, SETD2, SF3B1, SH2B3, SH2D1A, SHQ1, SLIT2, SLX4, SMAD2, SMAD3, SMAD4, SMARCA4, SMARCB1, SMARCD1, SMC1A, SMC3, SMO, SNCAIP, SOCS1, SOX10, SOX17, SOX2, SOX9, SPEN, SPOP, SPTA1, SRC, SRSF2, STAG1, STAG2, STAT3, STAT4, STAT5A, STAT5B, STK11, STK40, SUFU, SUZ12, SYK, TAF1, TBX3, TCF3, TCF7L2, TENT5C, TERC, TERT, TET1, TET2, TFE3, TFRC, TGFBR1, TGFBR2, TMEM127, TMPRSS2, TNFAIP3, TNFRSF14, TOP1, TOP2A, TP53, TP63, TRAF2, TRAF7, TSC1, TSC2, TSHR, U2AF1, VEGFA, VHL, VTCN1, WT1, XIAP, XPO1, XRCC2, YAP1, YES1, ZBTB2, ZBTB7A, ZFHX3, ZNF217, ZNF703, ZRSR2

Genes RNA: ABL1, AKT3, ALK, AR, AXL, BCL2, BRAF, BRCA1, BRCA2, CDK4, CSF1R, EGFR, EML4, ERBB2, ERG, ESR1, ETS1, ETV1, ETV4, ETV5, EWSR1, FGFR1, FGFR2, FGFR3, FGFR4, FLI1, FLT1, FLT3, JAK2, KDR, KIF5B, KIT, KMT2A, MET, MLLT3, MSH2, MYC, NOTCH1, NOTCH2, NOTCH3, NRG1, NTRK1, NTRK2, NTRK3, PAX3, PAX7, PDGFRA, PDGFRB, PIK3CA, PPARG, RAF1, RET, ROS1, RPS6KB1, TMPRSS2

*Análises podem variar de acordo com o tipo do tumor.

** Genes marcados como RNA contemplam a análise de fusões novas ou conhecidas.

***Sujeito a alterações sem aviso prévio. Versão: outubro de 2026.

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